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Mass Spectrometry Group at HKPU

Contact Person: Dr. Yao Zhong-ping
   
Address: Rm. Y832, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong SAR.
   
Research Interests:
  1. Development of new mass spectrometry-based techniques
    • Development of new ionization techniques, e.g., ambient ionization techniques.
    • Development of novel sample preparation methods for ESI-MS and MALDI-MS analysis.
    • Development of mass spectrometric techniques for direct analysis of complex samples, e.g., food, biological tissue, clinical samples, and environmental samples.
  2. Characterization of Chinese medicinal herbs by mass spectrometry
  3. Study of non-covalent interactions using native mass spectrometry and hydrogen-deuterium exchange mass spectrometry
  4. Biomarkers discovery and mechanism studies of diseases using mass spectrometry-based proteomic and metabolomic approaches
Instrumentation:
  1. UPLC-Triple Quadrupole Mass Spectrometer (Waters Quattro Ultima mass spectrometer coupled with Waters ACQUITY UPLC)
    • Equipped with standard ESI source.
  2. HPLC-Quadrupole-Time of Flight mass spectrometers (1 unit of Waters Q-TOF2 mass spectrometer coupled with Waters CapLC and 1 unit of Applied Biosystems Qstar Pulsar mass spectrometer coupled with Perkin Eimer Series 200 HPLC)
    • Equipped with standard ESI, nano-ESI, and APCI sources.
  3. Matrix-Assisted Laser Desorption/Ionization Mass Spectrometer (Waters MALDI MicroMX mass spectrometer)
    • Equipped with standard delay-ion extraction and reflectron mirror
  4. Quadrupole GC/MS (Agilent 5975B series GC/MSD)
    • Equipped with standard EI/CI source and solid probe
  5. Time of Flight GC/MS (Waters GCT mass spectrometer coupled with Agilent 7890A GC)
    • Equipped with standard EI/CI source and solid probe
  6. Double focusing magnetic-sector mass spectrometer coupled with GC (Waters AutoSpec Premier mass spectrometer coupled with Agilent 5890 GC)
    • Equipped with standard EI/CI source
MS services:   No regular MS service   Yes, please contact __________

For Research collaboration, please contact Dr. Yao Zhong-ping at #3400-8792 (or bczpyao@inet.polyu.edu.hk)

 

 

 

 
 
 
 

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